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1

Mitochondria in cancer cells: what is so special about them?

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Trends in Cell Biology

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

2

Mitochondrial Oxidative Stress: Implications for Cell Death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Annual Review of Pharmacology

Year:

2007

Language:

english

File:

PDF, 461 KB

english, 2007

3

Mitochondria, oxidative stress and cell death

Martin Ott, Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2007

Language:

english

File:

PDF, 325 KB

english, 2007

4

Outer mitochondrial membrane permeabilization: an open-and-shut case?

Robertson, J D, Zhivotovsky, B, Gogvadze, V, Orrenius, S

Journal:

Cell Death & Differentiation

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

5

Release of mitochondrial DNA fragments from brain mitochondria of irradiated mice

Maxim Patrushev, Vitaliy Kasymov, Valeria Patrusheva, Tatiana Ushakova, Vladimir Gogvadze, Azhub I. Gaziev

Journal:

Year:

2006

Language:

english

File:

PDF, 112 KB

english, 2006

6

The role of Fe2+-induced lipid peroxidation in the initiation of the mitochondrial permeability transition

Vladimir Gogvadze, Patrick B Walter, Bruce N Ames

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

7

Contrasting effects of α-tocopheryl succinate on cisplatin- and etoposide-induced apoptosis

Kruspig, Björn, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Year:

2013

Language:

english

File:

PDF, 505 KB

english, 2013

8

Mesenchymal stem cells and hypoxia: Where are we?

Buravkova, L.B., Andreeva, E.R., Gogvadze, V., Zhivotovsky, B.

Journal:

Year:

2014

Language:

english

File:

PDF, 627 KB

english, 2014

9

Calcium and mitochondria in the regulation of cell death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 764 KB

english, 2015

10

Targeting Mitochondria in Fighting Cancer

Gogvadze, Vladimir

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 392 KB

english, 2011

11

2-Deoxyglucose has distinct and cell line-specific effects on the survival of different cancer cells upon antitumor drug treatment

Maximchik, Polina, Abdrakhmanov, Alibek, Inozemtseva, Evgeniya, Tyurin-Kuzmin, Pyotr A., Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

12

Involvement of Ca2+ and ROS in α-tocopheryl succinate-induced mitochondrial permeabilization

Vladimir Gogvadze, Erik Norberg, Sten Orrenius, Boris Zhivotovsky

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 770 KB

english, 2010

13

P040 Hypomethylation and apoptosis in 5-azacytidine treated myeloid cells

R. Khan, J. Schmidt-Mende, M. Karimi, A.-M. Forsblom, V. Gogvadze, M. Hassan, T.J. Ekström, B. Zhivotovsky, E. Hellström-Lindberg

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

14

YI1 Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF) targets

M. Nikpour, A. Pellagatti, A. Liu, M. Karimi, L. Malcovati, A.-M. Forsblom, V. Gogvadze, J.S. Wainscoat, M. Cazzola, B. Zhivotovsky, A. Grandien, J. Boultwood, E. Hellström-Lindberg

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

15

Raman spectroscopic study on the nature of weak components of the water stretching band

N.A. Chumaevskii, M.N. Rodnikova, J. Barthel, K.A. Solntzev, D.A. Sirotkin, G.V. Gogvadze

Journal:

Journal of Molecular Liquids

Year:

2002

File:

PDF, 318 KB

2002

16

A folding variant of human α-lactalbumin induces mitochondrial permeability transition in isolated mitochondria

Camilla Köhler, Vladimir Gogvadze, Anders Håkansson, Catharina Svanborg, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2001

Language:

english

File:

PDF, 476 KB

english, 2001

17

Novel strong tissue specific promoter for gene expression in human germ cells

Denis Kuzmin, Elena Gogvadze, Roman Kholodenko, Dawid P Grzela, Maxim Mityaev, Tatyana Vinogradova, Eugene Kopantzev, Galina Malakhova, Maria Suntsova, Dmitry Sokov, Zoltán Ivics, Anton Buzdin

Journal:

BMC Biotechnology

Year:

2010

Language:

english

File:

PDF, 970 KB

english, 2010

18

Mitochondrial permeability transition triggers the release of mtDNA fragments

M. Patrushev, V. Kasymov, V. Patrusheva, T. Ushakova, V. Gogvadze, A. Gaziev

Journal:

Cellular and Molecular Life Sciences

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

19

Cytotoxic activity of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide is underlain by DNA interchain cross-linking

A. B. Moshnikova, V. N. Afanasyev, O. V. Proussakova, S. Chernyshov, V. Gogvadze, I. P. Beletsky

Journal:

Cellular and Molecular Life Sciences

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

20

Retroelements and their impact on genome evolution and functioning

Elena Gogvadze, Anton Buzdin

Journal:

Cellular and Molecular Life Sciences

Year:

2009

Language:

english

File:

PDF, 454 KB

english, 2009

21

Resveratrol induces SIRT1- and energy–stress-independent inhibition of tumor cell regrowth after low-dose platinum treatment

My Björklund, Jeanette Roos, Vladimir Gogvadze, Maria Shoshan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 725 KB

english, 2011

22

Mitochondria as targets for chemotherapy

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2009

Language:

english

File:

PDF, 420 KB

english, 2009

23

Alteration of mitochondrial function and cell sensitization to death

Vladimir Gogvadze, Boris Zhivotovsky

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2007

Language:

english

File:

PDF, 241 KB

english, 2007

24

A New Mechanism of Retrogene Formation in Mammalian Genomes:In VivoRecombination during RNA Reverse Transcription

E. V. Gogvadze, A. A. Buzdin

Journal:

Molecular Biology

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

25

Multiple template switches on LINE-directed reverse transcription: The most probable formation mechanism for the double and triple chimeric retroelements in mammals

E. V. Gogvadze, A. A. Buzdin, E. D. Sverdlov

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

26

Hippocampal Neurons Exposed to the Environmental Contaminants Methylmercury and Polychlorinated Biphenyls Undergo Cell Death via Parallel Activation of Calpains and Lysosomal Proteases

Roshan Tofighi, Carolina Johansson, Matteo Goldoni, Wan Norhamidah Wan Ibrahim, Vladimir Gogvadze, Antonio Mutti, Sandra Ceccatelli

Journal:

Neurotoxicity Research

Year:

2011

Language:

english

File:

PDF, 624 KB

english, 2011

27

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF

Maryam Nikpour, Andrea Pellagatti, Anquan Liu, Mohsen Karimi, Luca Malcovati, Vladimir Gogvadze, Ann-Mari Forsblom, James S. Wainscoat, Mario Cazzola, Boris Zhivotovsky, Alf Grandien, Jacqueline Boult

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

28

An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death

Norberg, E, Gogvadze, V, Ott, M, Horn, M, Uhlén, P, Orrenius, S, Zhivotovsky, B

Journal:

Cell Death & Differentiation

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

29

p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis

Sayan, A E, Sayan, B S, Gogvadze, V, Dinsdale, D, Nyman, U, Hansen, T M, Zhivotovsky, B, Cohen, G M, Knight, R A, Melino, G

Journal:

Year:

2008

Language:

english

File:

PDF, 370 KB

english, 2008

30

Early mitochondrial alterations in ATRA-induced cell death

Schmidt-Mende, J, Gogvadze, V, Hellström-Lindberg, E, Zhivotovsky, B

Journal:

Cell Death & Differentiation

Year:

2005

Language:

english

File:

PDF, 321 KB

english, 2005

31

Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

Robertson, John D, Gogvadze, Vladimir, Kropotov, Andrey, Vakifahmetoglu, Helin, Zhivotovsky, Boris, Orrenius, Sten

Journal:

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

32

Investigation of Calcium Accumulation in Mitochondria in Cells Undergoing Apoptosis

V.E. Galitovsky, V.G. Gogvadze

Journal:

Biochemistry (Moscow)

Year:

2001

Language:

english

File:

PDF, 213 KB

english, 2001

33

Cytochromec: the Achilles’ heel in apoptosis

Kulikov, A. V., Shilov, E. S., Mufazalov, I. A., Gogvadze, V., Nedospasov, S. A., Zhivotovsky, B.

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 492 KB

english, 2012

34

Targeting mitochondria byα-tocopheryl succinate kills neuroblastoma cells irrespective ofMycNoncogene expression

Kruspig, Björn, Nilchian, Azadeh, Bejarano, Ignacio, Orrenius, Sten, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

35

Genome-wide targeted search for human specific and polymorphic L1 integrations

Anton Buzdin,Svetlana Ustyugova,Elena Gogvadze,Yuri Lebedev…

Journal:

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

36

Regulation of the rate of respiration and oxidative phosphorylation in liver mitochondria from hibernating ground squirrels, Citallus undulatus

N.N. Brustovetsky, E.I. Mayevsky, E.V. Grishina, V.G. Gogvadze, Z.G. Amerkhanov

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1989

Language:

english

File:

PDF, 477 KB

english, 1989

37

The effect of dietary supplements on gene expression in mice tissues

Tatyana Ushakova, Hovsep Melkonyan, Larisa Nikonova, Nicolai Mudrik, Vladimir Gogvadze, Alexandra Zhukova, Azhub I. Gaziev, Robert Bradbury

Journal:

Free Radical Biology and Medicine

Year:

1996

Language:

english

File:

PDF, 572 KB

english, 1996

38

Mitochondrial regulation of apoptotic cell death

Vladimir Gogvadze, Sten Orrenius

Journal:

Chemico-Biological Interactions

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

39

Hypomethylation and apoptosis in 5-azacytidine–treated myeloid cells

Rasheed Khan, Jan Schmidt-Mende, Mohsen Karimi, Vladimir Gogvadze, Moustapha Hassan, Tomas J. Ekström, Boris Zhivotovsky, Eva Hellström-Lindberg

Journal:

Experimental Hematology

Year:

2008

Language:

english

File:

PDF, 882 KB

english, 2008

40

Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing

Erik Norberg, Vladimir Gogvadze, Helin Vakifahmetoglu, Sten Orrenius, Boris Zhivotovsky

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 792 KB

english, 2010

41

Multiple roles of microsomal glutathione transferase 1 in cellular protection: A mechanistic study

Katarina Johansson, Julia Järvliden, Vladimir Gogvadze, Ralf Morgenstern

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 898 KB

english, 2010

42

Mitochondria as targets for cancer chemotherapy

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Seminars in Cancer Biology

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

43

Arsenic stimulates release of cytochrome c from isolated mitochondria via induction of mitochondrial permeability transition

Juanita Bustamante, Leta Nutt, Sten Orrenius, Vladimir Gogvadze

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

44

Functional human endogenous retroviral LTR transcription start sites are located between the R and U5 regions

Elena Kovalskaya, Anton Buzdin, Elena Gogvadze, Tatyana Vinogradova, Eugene Sverdlov

Journal:

Year:

2006

Language:

english

File:

PDF, 260 KB

english, 2006

45

Control of the pyridine nucleotide-linked Ca2+ release from mitochondria by respiratory substrates

Vladimir Gogvadze, Matthias Schweizer, Christoph Richter

Journal:

Year:

1996

Language:

english

File:

PDF, 583 KB

english, 1996

46

Modification of gene expression by dietary antioxidants in radiation-induced apoptosis of mice splenocytes

Tatyana Ushakova, Hovsep Melkonyan, Larisa Nikonova, Vladimir Afanasyev, Azhub I Gaziev, Nikolai Mudrik, Robert Bradbury, Vladimir Gogvadze

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

47

Fe2+ Induces a Transient Ca2+ Release from Rat Liver Mitochondria

Vladimir Gogvadze, Patrick B. Walter, Bruce N. Ames

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

48

Nitric-Oxide Kills Hepatocytes by Mobilizing Mitochondrial Calcium

C. Richter, V. Gogvadze, R. Schlapbach, M. Schweizer, J. Schlegel

Journal:

Biochemical and Biophysical Research Communications

Year:

1994

File:

PDF, 326 KB

1994

49

Nitric Oxide (Nitrogen Monoxide, No) Stimulates Insulin Secretion by Inducing Calcium Release from Mitochondria

R. Laffranchi, V. Gogvadze, C. Richter, G.A. Spinas

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 390 KB

1995

50

Tributyltin Causes Cytochrome c Release from Isolated Mitochondria by Two Discrete Mechanisms

Vladimir Gogvadze, Helene Stridh, Sten Orrenius, Ian Cotgreave

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002